PPAR modulation of kinase-linked receptor signaling in physiology and disease.

نویسندگان

  • Nicolas Rotman
  • Walter Wahli
چکیده

Kinase-linked receptors and nuclear receptors connect external cues to gene transcription. Among nuclear receptors, peroxisome proliferator-activated receptors (PPARs) are of special interest in relation to widespread human diseases. Mapping out connections between PPARs and kinase-linked receptor signaling is central to better understand physiological and pathophysiological processes and to better define therapeutic strategies. This is the aim of the present review.

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عنوان ژورنال:
  • Physiology

دوره 25 3  شماره 

صفحات  -

تاریخ انتشار 2010